Welcome to the Paulson Lab!

University of Michigan Health System

Department of Neurology

Henry L Paulson Laboratory

Biomedical Sciences Research Building

109 Zina Pitcher Place, Ann Arbor, MI 48109

Room Number: 4160

What's New

Congratulations to Hank Paulson for being elected to the

National Academy of Medicine!

Dr. Paulson was elected to the NAM in 2020 for his work in making fundamental discoveries regarding protein aggregation and nucleotide repeat expansions as causes of neurodegenerative diseases, and pioneering novel therapeutic strategies, including nucleotide-based gene silencing and harnessing the cell’s own quality-control machinery, for this group of devastating disorders.


Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins. Sci Rep. 2021 Jan

PMID: 33431932

Ubiquilin-2 differentially regulates polyglutamine disease proteins. Hum Mol Genet. 2020 Aug

PMID: 32681165

Modeling UBQLN2-mediated neurodegenerative disease in mice: Shared and divergent properties of wild type and mutant UBQLN2 in phase separation, subcellular localization, altered proteostasis pathways, and selective cytotoxicity. Neurobiol Dis. 2020 Sep

PMID: 32653673


Hank Paulson was awarded an NIH R35 grant in 2021 to investigate "mechanisms of neurodegenerative diseases: intersections with ubiquitin pathways"!

Hari passed his preliminary examination and has been awarded the Rackham pre-candidate grant!

Hanna was selected as an awardee for the Michigan Alzheimer’s Disease Center (MADC) Pilot Project Program!

Hank Paulson received the Movement Disorders Research Award in 2020 from the American Academy of Neurology for his discoveries regarding the mechanisms and treatment of hereditary ataxia.

Hank also received the Landis Award for Outstanding Mentorship from the NINDS. As stated by NINDS: "Trainees often equated his mentorship style as treating people equally and with unwavering respect."

Stephanie Sandoval-Pistorius has been selected for the 2020 NIH Blueprint Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award!

Welcome Jeremy and goodbye Sveta!

We welcome Jeremy Dortch, a first-year PIBS rotation student! We also bid farewell to lab manager Svetlana Fischer who is retiring. Happy retirement, Sveta!