Welcome to the Paulson Lab!

University of Michigan Health System

Department of Neurology

Henry L Paulson Laboratory

Biomedical Sciences Research Building

109 Zina Pitcher Place, Ann Arbor, MI 48109

Room Number: 4160


What's New

Congratulations to Dr. Paulson for being elected to the

National Academy of Medicine!

Dr. Paulson is being elected to the NAM for his work in making fundamental discoveries regarding protein aggregation and nucleotide repeat expansions as causes of neurodegenerative diseases, and pioneering novel therapeutic strategies, including nucleotide-based gene silencing and harnessing the cell’s own quality-control machinery, for this group of devastating disorders.

RECENT PUBLICATIONS

Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins. Sci Rep. 2021 Jan

PMID: 33431932

Ubiquilin-2 differentially regulates polyglutamine disease proteins. Hum Mol Genet. 2020 Aug

PMID: 32681165

Modeling UBQLN2-mediated neurodegenerative disease in mice: Shared and divergent properties of wild type and mutant UBQLN2 in phase separation, subcellular localization, altered proteostasis pathways, and selective cytotoxicity. Neurobiol Dis. 2020 Sep

PMID: 32653673


RECENT AWARDS

Dr. Paulson received the Landis Award for Outstanding Mentorship from the NINDS. As stated by NINDS: "Trainees often equated his mentorship style as treating people equally and with unwavering respect."


Stephanie Sandoval-Pistorius has been selected for the 2020 NIH Blueprint Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award! Stephanie has also received funding for her NRSA! We couldn't be more proud of all her hard work!

Congratulations Hanna!

Hanna was selected as an awardee for the Michigan Alzheimer’s Disease Center (MADC) Pilot Project Program!