Welcome to the Paulson Lab!

University of Michigan Health System

Department of Neurology

Henry L Paulson Laboratory

Biomedical Sciences Research Building

109 Zina Pitcher Place, Ann Arbor, MI 48109

Room Number: 4160

What's New

Congratulations to Dr. Paulson for being elected to the

National Academy of Medicine!

Dr. Paulson is being elected to the NAM for his work in making fundamental discoveries regarding protein aggregation and nucleotide repeat expansions as causes of neurodegenerative diseases, and pioneering novel therapeutic strategies, including nucleotide-based gene silencing and harnessing the cell’s own quality-control machinery, for this group of devastating disorders.


Antisense oligonucleotide therapy rescues aggresome formation in a novel spinocerebellar ataxia type 3 human embryonic stem cell line. July 2019, Stem Cell Res.

PMID: 31374463

Differential toxicity of ataxin-3 isoforms in Drosophila models of Spinocerebellar Ataxia Type 3. July 2019, Neurobiol Dis.

PMID: 31310802


We are excited to welcome our new graduate student, Harihar Milaganur Mohan, and postdoctoral fellow, Hanna Trzeciakiewicz, to the Paulson Lab!


Graduate student Stephanie Sandoval-Pistorius has been selected for the 2020 NIH Blueprint Diversity Specialized Predoctoral to Posdoctoral Advancement in Neuroscience (D-SPAN) Award! Stephanie has also received funding for her NRSA! We couldn't be more proud of all her hard work!


Thank you to Haiyang Luo, M.D., Ph.D., a visiting post-doctoral fellow from China who is investigating the role of wt/expanded ataxin-3 in regulating different poly-ubiquitin species or different poly-ubiquitinated substrates. We will miss you and enjoyed having you in the lab!