Current Members

Henry L. Paulson, MD, PhD
Phone: (734) 615-5632

Henry L. Paulson, MD, PhD, is the Lucile Groff Professor of Neurology for Alzheimer’s Disease and Related Disorders in the Department of Neurology at the University of Michigan and a Taubman Scholar in the A. Alfred Taubman Medical Research Institute. Dr. Paulson joined the U-M faculty in 2007, where he directs the programs in degenerative brain diseases and the Michigan Alzheimer’s Disease Center. Dr. Paulson received his MD and PhD from Yale University in 1990, then completed a neurology residency and neurogenetics/movement disorders fellowships at the University of Pennsylvania. From 1997 to 2007, he was on the faculty at the University of Iowa. Dr. Paulson’s research interests concern the causes and treatment of age-related neurodegenerative diseases, with an emphasis on Alzheimer’s disease and other dementias, hereditary ataxia, and polyglutamine diseases. Dr. Paulson serves on the scientific advisory boards of numerous disease-related national organizations, and is past Chairperson of the Board of Scientific Counselors at the National Institute for Neurological Disorders and Stroke at the National Institutes of Health. 

Svetlana Fischer
Research Lab Specialist/Lab Manager
Phone:  (734) 615-6156

Svetlana received her Master of Science degree in Biology from Tomsk State University in Russia. 

Lisa Sharkey, PhD
Research Assistant Professor
Phone: (734) 615-6156

Dr. Sharkey completed her Ph.D in Neuroscience at the University of Wisconsin-Madison. She has completed 2 postdoctoral fellowships studying the molecular mechanisms of neurological disease at the Scripps Research Institute in La Jolla, CA, Department of Molecular and Cellular Neuroscience, and at the University of Michigan in the Department of Human Genetics. In her current position in Dr. Paulson's laboratory she is interested in studying the mechanisms of neurodegeneration underlying two common forms of dementia: Alzheimer's Disease and Frontotemporal Dementia (FTD). Ubiquillin2 (Ub2) is a member of a family of proteins containing ubiquitin-like domains that has been implicated in the trafficking of proteins tagged for degradation to the proteasome. Mutations in Ub2 have been shown to cause FTD and Amyotrophic Lateral Sclerosis (ALS). In order to investigate the function of this poorly understood protein, Dr. Sharkey has developed transgenic mouse lines expressing WT and mutant forms of Ub2. Her goal is to use these mice to understand the cellular role of Ub2 in protein quality control both in health and disease states.

Lauren Moore
Graduate Student                                       

Lauren is a doctoral student in the Neuroscience Graduate Program at the University 
of Michigan. She received her Bachelor of Science degree in Biomedical Physics at Northeastern University in 2013 and joined the Paulson lab in June 2014. Her research focuses on developing and testing oligonucleotide-based approaches to silencing ataxin-3 translation in cellular and rodent models of spinocerebellar ataxia type 3.

Julia Gerson, PhD
Postdoctoral Fellow

Julia completed her doctoral studies in 2016 at the University of Texas Medical Branch where she studied tau oligomer structures in neurodegenerative disease and evaluated the efficacy of immunotherapy against oligomeric tau in mouse models. In the Paulson lab, Julia investigates the role of protein quality control protein, UBQLN2, in regulating tau and other common aggregating proteins in neurodegenerative disease.

Rebecca Stone

Administrative Assistant
Phone: (734) 615-5632
Fax: (734) 647-9777


Our Team of Undergraduate Students:

Kate Blumenstein

Emily Crowley

Michelle Hoang

Emily Shaw

Aidan Snell

Jacqueline Welday

Cade Cantu

Madison Salvato

Danielle DiFranco

Maurice Tohme

Hannah Perlstein

Zaid Haque

Nicholas Stec

Mary Claire Manley

Vivian Yang

Keyshla Negron 

Kenneth O'donnell

Amanda Pierce

Subpages (1): Affiliated Faculty